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In vitro tolerance tests

for cosmetic finished products

Accrédité BPL, BIO-HC accompagne depuis plus de 20 ans les entreprises cosmétiques dans l'évaluation de la tolérance et de la sécurité de leurs produits finis. Des tests réglementaires réalisables rapidement sont à votre disposition pour compléter vos dossiers de sécurité.
Our in vitro tolerance models for cosmetic
Skin irritation tests
Patch test and reconstructed human epidermis
Ocular irritation tests
HetCam, neutral red, agarose gel, reconstructed corneal epithelium, ...
Phototoxic potential
3T3 or L929 cell model, reconstructed human epidermis, ...
Labial and buccal tolerance
Reconstructed human oral epithelium
Gingival tolerance
Reconstructed human gingival epithelium
Vaginal tolerance
Reconstructed human vaginal epithelium

Our models

Our team works on a full range of analytical models to test the tolerance of finished cosmetic products. From the most basic unit of living things, the single cell, to the complex tissues of skin explants, our experienced teams help you choose the test method that’s right for you


Using cellular models for safety assessment enables you to rapidly test the tolerance of your finished products.

Reconstructed epitheliums

From ocular tolerance on reconstructed epithelium to tolerance testing on specific mucous membranes, we can assess the safety of all categories of cosmetic products.

The BIO-HC difference


The methods used in our laboratory to assess product safety adhere strictly to French government guidelines and the principles of Good Laboratory Practice (GLP).


Flexible scheduling enables BIO-HC to analyze your samples within the desired timeframe. Call today to ask about deadline feasibility.


Certified GLP, BIO-HC has the scientific competence it takes to serve your R&D needs and develop its own research models.

Ask for a quote

Aloïs, Technical and commercial Affairs
A trained scientist and management graduate, Aloïs will help you define your needs and answer any questions you may have to launch a study that best suits your needs and budget.